曲喹辛
| 曲喹辛 | |
|---|---|
| |
| IUPAC名 9,10-Dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one | |
| 识别 | |
| CAS号 | 79855-88-2 
|
| PubChem | 5537 |
| ChemSpider | 5336 |
| SMILES |
|
| InChI |
|
| InChIKey | MCMSJVMUSBZUCN-UHFFFAOYSA-N |
| 性质 | |
| 化学式 | C24H27N3O3 |
| 摩尔质量 | 405.49 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
曲喹辛（英語：Trequinsin，也译为“曲林菌素”）是一种含氮有机化合物，分子式C24H27N3O3，可作为磷酸二酯酶抑制药[1]，在体外实验（in vitro）中能增强精子活性[2]。
参考文献
[编辑]- ^ Whitaker, RM; Wills, LP; Stallons, LJ; Schnellmann, RG. CGMP-Selective Phosphodiesterase Inhibitors Stimulate Mitochondrial Biogenesis and Promote Recovery from Acute Kidney Injury. The Journal of Pharmacology and Experimental Therapeutics. 2013, 347 (3): 626–34. PMC 3836317
. PMID 24042162. doi:10.1124/jpet.113.208017.
- ^ McBrinn, RC; Fraser, J; Hope, AG; Gray, DW; Barratt, CLR; Martins da Silva, SJ; Brown, SG. Novel pharmacological actions of trequinsin hydrochloride improve human sperm cell motility and function.. British journal of pharmacology. 2019-12, 176 (23): 4521–4536. PMID 31368510. doi:10.1111/bph.14814.
