羥甲芬太尼

羥甲芬太尼
臨床資料
ATC碼	未分配;
法律規範狀態
法律規範	加：Schedule I; 德：Anlage I; 英：Class A; 美：附表I; UN：Psychotropic Schedule I;
識別資訊
	IUPAC命名法 N-[1-(2-hydroxy-2-phenylethyl)-3-methylpiperidin-4-yl]-N-phenylpropanamide; ;
CAS號	78995-14-9
PubChem CID	62279;
DrugBank	DB01570;
ChemSpider	56080 ;
UNII	Y8263089ZX;
KEGG	C22750;
ChEMBL	ChEMBL333410;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID50868495 ;
化學資訊
化學式	C23H30N2O2
摩爾質量	366.51 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES CCC(=O)N(c1ccccc1)C2CCN(CC2C)CC(O)c3ccccc3;
	InChI InChI=1S/C23H30N2O2/c1-3-23(27)25(20-12-8-5-9-13-20)21-14-15-24(16-18(21)2)17-22(26)19-10-6-4-7-11-19/h4-13,18,21-22,26H,3,14-17H2,1-2H3 ; Key:FRPRNNRJTCONEC-UHFFFAOYSA-N ;

羥甲芬太尼（英語：Ohmefentanyl，也稱為β-羥基-3-甲基芬太尼，β-hydroxy-3-methylfentanyl，縮寫OMF，研發代號：RTI-4614-4）是一種含氮有機化合物，化學式C₂₃H₂₀N₂O₂，屬於芬太尼衍生物^[1]，能作為類阿片鎮痛藥^[2]^[3]。

參考文獻

^ Rothman RB, Xu H, Seggel M, Jacobson AE, Rice KC, Brine GA, Carroll FI. RTI-4614-4: an analog of (+)-cis-3-methylfentanyl with a 27,000-fold binding selectivity for mu versus delta opioid binding sites. Life Sciences. April 1991, 48 (23): PL111–PL116. PMID 1646357. doi:10.1016/0024-3205(91)90346-D.
^ Brine GA, Stark PA, Liu Y, Carroll FI, Singh P, Xu H, Rothman RB. Enantiomers of diastereomeric cis-N-[1-(2-hydroxy-2-phenylethyl)- 3-methyl-4-piperidyl]-N-phenylpropanamides: synthesis, X-ray analysis, and biological activities. Journal of Medicinal Chemistry. April 1995, 38 (9): 1547–1557. PMID 7739013. doi:10.1021/jm00009a015.
^ Wang ZX, Zhu YC, Jin WQ, Chen XJ, Chen J, Ji RY, Chi ZQ. Stereoisomers of N-[1-hydroxy-(2-phenylethyl)-3-methyl-4-piperidyl]- N-phenylpropanamide: synthesis, stereochemistry, analgesic activity, and opioid receptor binding characteristics. Journal of Medicinal Chemistry. September 1995, 38 (18): 3652–3659. PMID 7658453. doi:10.1021/jm00018a026.