過氧乙酸

過氧乙酸
過氧乙酸	過氧乙酸
	IUPAC名; ethaneperoxoic acid
別名	過氧醋酸、過乙酸、過醋酸
識別
縮寫	PAA
CAS號	79-21-0
PubChem	6585
ChemSpider	6336
SMILES	CC(=O)OO;
InChI	1/C2H4O3/c1-2(3)5-4/h4H,1H3;
InChIKey	KFSLWBXXFJQRDL-UHFFFAOYAD
RTECS	SD8750000
KEGG	D03467
性質
化學式	C2H4O3
摩爾質量	76.05 g·mol⁻¹
外觀	無色液體
密度	1.13 g/ml (液態)
熔點	0.1 °C
沸點	105 °C
pKa	8.20
黏度	3.280
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

過氧乙酸（俗名過醋酸，英文：Peracetic acid／peroxyacetic acid／PAA）是有機過氧酸家族的成員。透明液體，有典型乙酸氣味，是強氧化劑。^[1]

歷史

過醋酸用作消毒劑已有百年歷史^[2]，1902年Freer與Novy於美國化學期刊（American Chemical Journal，ACJ）首次發表過醋酸能有效抑制細菌及細菌孢子活性。1949年美國細菌學協會（American Bacteriological Association）指出有報導比較了滅菌劑23種成份，當中認為過醋酸最有效^[3]。

應用

現今過醋酸在歐洲大量用於消毒食品工業、釀酒工業、水處理系統及淨水系統；在醫療領域，過醋酸用於消毒可重用醫療器械、血液透析設備、醫院織物洗滌廠（按德國羅伯特·科赫研究所清單程序）。

過醋酸從1955年即用作消毒劑或滅菌劑，大部份用於處理食品及污水，亦曾用於塑膠隔離用具或消毒醫療物品。它可殺死細菌繁殖體、黴菌、細菌孢子及病毒^[4]，快速廣效；濃度低於百萬份之1時，可在5分鐘內抑制革蘭氏陽性菌、革蘭氏陰性菌、黴菌及酵母菌，亦証實可殺死小兒麻痺病毒、輪狀病毒、B型肝炎、HIV病毒。^[5]^[6]^[7]

化學特性

過氧乙酸高濃度時無色、有強烈刺激味、有腐蝕性，高溫加熱分解，由醋酸及雙氧水反應生成，殺菌作用機理為釋出自由氧及氫基，最終分解成氧氣、水及醋酸。^[2]大多市售過醋酸濃5%、10%及15%。

環保優勢

過醋酸在自然環境中降解為醋酸，再降解為其它物質^[8]，常用於處理環境河川水。^[2]

參考資料

^ 邢其毅等。. 《基础有机化学》第三版上册. 北京：高等教育出版社. 2005年. ISBN 7-04-016637-2.
^ ^2.0 ^2.1 ^2.2 Dr. Holger Biering. More than 100 years of Peracetic Acid. Journal for Hygiene in Hospitals and Medical Practice.
^ I.J. Hutchings u. H. Xezones: Proceedings of the 49th annual meeting of the Society of American Bacteriology, Cincinatti, OH (1949)
^ BSG Endoscopy committee working party. Cleaning and disinfection of equipment for gastrointestinal endoscopy. Report of a Working Party of the British Society of Gastroen terology Endoscopy Committee. Gut, 1998; 42:585-93.
^ Ossia-Ongagna Y, Sabatier R. Comparison of in vitro activity of six disinfectants on bacteria from contamination in haemodialysis water. J Pharm Belg 1993; 48: 341-5.
^ Baldry MGC. The bactericidal, fungicidal and sporicidal properties of hydrogen peroxide and pancreatic acid. J Appl Bacteriol 1983; 54:417-23.
^ Lynam PA, Babb JR, Fraise A. Comparison of the mycobactericidal activity of 2% alkaline glutaraldehyde and Nu-Cidex (0.35% peracetic acid). J Hosp Infect 1995; 30: 237-40.
^ ECETOC-Monographie JACC No. 40 »Per- acetic Acid and its Equilibrium Solutions« (2001)

[1] 邢其毅等。. 《基础有机化学》第三版上册. 北京：高等教育出版社. 2005年. ISBN 7-04-016637-2.

[:0-2] 2.0 ^2.1 ^2.2 Dr. Holger Biering. More than 100 years of Peracetic Acid. Journal for Hygiene in Hospitals and Medical Practice.

[3] I.J. Hutchings u. H. Xezones: Proceedings of the 49th annual meeting of the Society of American Bacteriology, Cincinatti, OH (1949)

[4] BSG Endoscopy committee working party. Cleaning and disinfection of equipment for gastrointestinal endoscopy. Report of a Working Party of the British Society of Gastroen terology Endoscopy Committee. Gut, 1998; 42:585-93.

[5] Ossia-Ongagna Y, Sabatier R. Comparison of in vitro activity of six disinfectants on bacteria from contamination in haemodialysis water. J Pharm Belg 1993; 48: 341-5.

[6] Baldry MGC. The bactericidal, fungicidal and sporicidal properties of hydrogen peroxide and pancreatic acid. J Appl Bacteriol 1983; 54:417-23.

[7] Lynam PA, Babb JR, Fraise A. Comparison of the mycobactericidal activity of 2% alkaline glutaraldehyde and Nu-Cidex (0.35% peracetic acid). J Hosp Infect 1995; 30: 237-40.

[8] ECETOC-Monographie JACC No. 40 »Per- acetic Acid and its Equilibrium Solutions« (2001)

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