4-乙基叔丁苯

4-乙基叔丁苯
別名	對乙基叔丁苯; 4-叔丁基乙苯
識別
CAS號	7364-19-4
性質
化學式	C12H18
摩爾質量	162.27 g·mol−1
密度	0.8641 g·cm−3（20 °C）
熔點	−38.35 °C（234.80 K）
沸點	212.1 °C（485.2 K）
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

4-乙基叔丁苯是一種有機化合物，化學式為C₁₂H₁₈，它可由4-叔丁基苯乙烯在鈀（或納米鎳^[2]）催化下加氫得到。^[3]在乙酸亞銅的催化下，它和三甲基氰矽烷、N-氟代二(苯磺醯)胺反應，苄位氫氰化，得到(αS)-α-甲基-4-叔丁基苯乙腈。^[4]它和氟硼酸硝醯在乙腈中反應，可以得到3-硝基-4-乙基叔丁苯。^[5]

參考文獻

^ ^1.0 ^1.1 ^1.2 Schlatter, Maurice J.; Clark, Robert D. t-Alkyl Groups. I. Orientation of t-Alkylation Products of Toluene and Ethylbenzene. Journal of the American Chemical Society (American Chemical Society (ACS)). 1953, 75 (2): 361–369. ISSN 0002-7863. doi:10.1021/ja01098a032.
^ Mara Klarner, Sandra Bieger, Markus Drechsler, Rhett Kempe. Chemoselective Hydrogenation of Olefins Using a Nanostructured Nickel Catalyst. Zeitschrift für anorganische und allgemeine Chemie. 2021-11-25, 647 (22): 2157–2161 [2021-12-24]. ISSN 0044-2313. doi:10.1002/zaac.202100124. （原始內容存檔於2021-12-24）（英語）.
^ A. Sravanth Kumar, K. K. R. Datta, T. Srinivasa Rao, K. V. Raghavan, M. Eswaramoorthy, B. V. Subba Reddy. Pd-Aminoclay Nanocomposite as an Efficient Recyclable Catalyst for Hydrogenation and Suzuki Cross Coupling Reactions. Journal of Nanoscience and Nanotechnology. 2012-03-01, 12 (3): 2000–2007 [2021-12-24]. ISSN 1533-4880. doi:10.1166/jnn.2012.6132 （英語）.
^ Wen Zhang, Fei Wang, Scott D. McCann, Dinghai Wang, Pinhong Chen, Shannon S. Stahl, Guosheng Liu. Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay. Science. 2016-09-02 [2021-12-24]. PMC 5488708 . PMID 27701109. doi:10.1126/science.aaf7783 （英語）.
^ Pier F. Cirillo, Eugene R. Hickey, Neil Moss, Steffen Breitfelder, Raj Betageri, Tazmeen Fadra, Faith Gaenzler, Thomas Gilmore, Daniel R. Goldberg, Victor Kamhi, Thomas Kirrane, Rachel R. Kroe, Jeffrey Madwed, Monica Moriak, Matthew Netherton, Christopher A. Pargellis, Usha R. Patel, Kevin C. Qian, Rajiv Sharma, Sanxing Sun, Alan Swinamer, Carol Torcellini, Hidenori Takahashi, Michele Tsang, Zhaoming Xiong. Discovery and characterization of the N-phenyl-N′-naphthylurea class of p38 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009-05, 19 (9): 2386–2391 [2021-12-24]. doi:10.1016/j.bmcl.2009.03.104. （原始內容存檔於2020-02-18）（英語）.

[Maurice-1] 1.0 ^1.1 ^1.2 Schlatter, Maurice J.; Clark, Robert D. t-Alkyl Groups. I. Orientation of t-Alkylation Products of Toluene and Ethylbenzene. Journal of the American Chemical Society (American Chemical Society (ACS)). 1953, 75 (2): 361–369. ISSN 0002-7863. doi:10.1021/ja01098a032.

[2] Mara Klarner, Sandra Bieger, Markus Drechsler, Rhett Kempe. Chemoselective Hydrogenation of Olefins Using a Nanostructured Nickel Catalyst. Zeitschrift für anorganische und allgemeine Chemie. 2021-11-25, 647 (22): 2157–2161 [2021-12-24]. ISSN 0044-2313. doi:10.1002/zaac.202100124. （原始內容存檔於2021-12-24）（英語）.

[3] A. Sravanth Kumar, K. K. R. Datta, T. Srinivasa Rao, K. V. Raghavan, M. Eswaramoorthy, B. V. Subba Reddy. Pd-Aminoclay Nanocomposite as an Efficient Recyclable Catalyst for Hydrogenation and Suzuki Cross Coupling Reactions. Journal of Nanoscience and Nanotechnology. 2012-03-01, 12 (3): 2000–2007 [2021-12-24]. ISSN 1533-4880. doi:10.1166/jnn.2012.6132 （英語）.

[4] Wen Zhang, Fei Wang, Scott D. McCann, Dinghai Wang, Pinhong Chen, Shannon S. Stahl, Guosheng Liu. Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay. Science. 2016-09-02 [2021-12-24]. PMC 5488708 . PMID 27701109. doi:10.1126/science.aaf7783 （英語）.

[5] Pier F. Cirillo, Eugene R. Hickey, Neil Moss, Steffen Breitfelder, Raj Betageri, Tazmeen Fadra, Faith Gaenzler, Thomas Gilmore, Daniel R. Goldberg, Victor Kamhi, Thomas Kirrane, Rachel R. Kroe, Jeffrey Madwed, Monica Moriak, Matthew Netherton, Christopher A. Pargellis, Usha R. Patel, Kevin C. Qian, Rajiv Sharma, Sanxing Sun, Alan Swinamer, Carol Torcellini, Hidenori Takahashi, Michele Tsang, Zhaoming Xiong. Discovery and characterization of the N-phenyl-N′-naphthylurea class of p38 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009-05, 19 (9): 2386–2391 [2021-12-24]. doi:10.1016/j.bmcl.2009.03.104. （原始內容存檔於2020-02-18）（英語）.

[1]

[2]

[3]

[4]

[5]